Hyaline Cartilage

Hyaline means “glass-like” or “transparent” because of how it looks under the microscope.  It is the most common cartilage and can be found in locations such as trachea, articular surfaces of bones, larynx and nasal septum.  Even though it’s called “glass-like”, the extracellular matrix contains collagen but normally cannot be seen under light microscopy.  Just like other types of cartilage, the major cell type found is chondrocyte.

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Trachea, t.s.  (TM: 100x, pictures taken with a Nikon Plan Apo 10/0.4 on Sony A7ii)
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Same specimen as above, showing chondrocytes in their lacunae surrounded by the matrix that appears to be “glass-like” with this staining.  (TM: 400x, picture taken with a Zeiss Planapo 40/1.0 Oil on Sony A7ii)
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Same view as above.  (TM: 630x, picture taken with a Zeiss Planapo 63/1.4 Oil on Sony A7ii)

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