Stratified Squamous Epithelium, non-Keratinized

Stratified epithelium is classified by the cell type on the uppermost layer.  Notice that is true for the pictures shown below.  They are typically found in locations where constant abrasion is likely, such as mouth, esophagus and vagina.  The epithelium at these locations do not have thick layers of Kertain on top, and thus are classified as non-Keratinized.  In other words, these are moisturized lining.

Because the uppermost layer of cells are regularly sloughed off by abrasions, they are constantly replenished by an actively dividing basal layer.  The basal layers tend to be more cuboidal in shape and the cells being pushed outward gradually take on the flattened morphology.

Dog Esophagus.jpg
Dog esophagus.  Notice the lumen is lined with a darkened layer (stratified squamous epithelium) (TM: ~2.5x, picture taken with a Nikon Coolscan V Slide scanner)
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Esophagus from the lower esophageal portion.  (TM: 400x, picture taken with a Zeiss 40/1.0 Oil on Sony A7ii)
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Human Vagina.  Notice the nuclei of the basal cells form the demarcation between the epithelial tissue above and the connective tissue below.  (TM: 100x, picture taken with a Nikon Planapo 10/0.4 on Sony A7ii)
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Human vagina.  Notice the difference in morphology between the uppermost cells and the cuboidal shaped basal cells that are arranged in a line.  (TM: 400x, picture taken with a Zeiss Planapo 40/1.0 Oil on Sony A7ii)
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Esophagus.  Notice the similar morphology comparing to the vagina specimen above.  (TM: 400x, picture taken with a Zeiss Planapo 40/1.0 Oil on Sony A7ii)

 

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